Modifier symbols: ⌘ Command, ⇧ Shift, ⌥ Option, ⌃ Control.
| Key | Tool | Key | Tool |
|---|---|---|---|
| N | Pencil | E | Eraser |
| P | Pen | L | Line |
| A | Airbrush | R | Rectangle |
| S | Smudge | O | Oval |
| C | Colour Shift | D | Eyedropper |
| G | Clone | M | Select Rectangle |
| K | Fill | I | Select Oval |
| W | Select Wand | U | Select Freehand |
| Y | Select Polygon | V | Vector Select |
| B | Poly Line | Space | Move (hold from any tool) |
| Pixel Perfect strokes | F |
| Next / previous palette colour | X / ⇧X |
| Decrease / increase brush size | [ / ] |
| Decrease / increase dither level | , / . |
| Flip dither level | / |
| Layer opacity 10%–100% | 1–0 |
| New / Open / Save / Close | ⌘N / ⌘O / ⌘S / ⌘W |
| Import… | ⌘I |
| Export as Image… | ⌘E |
| Export as Sheet… | ⇧⌘E |
| Share as Image… | ⌥⌘S |
| Open With… | ⇧⌘O |
| Undo / Redo | ⌘Z / ⇧⌘Z |
| Cut / Copy / Paste as New Layer | ⌘X / ⌘C / ⌘V |
| Copy Cursor Position | ⌃⌥⌘C |
| Select All / Select None | ⌘A / ⌘D |
| Select All Pixels on Layer | ⇧⌘A |
| Invert Selection | ⇧⌘I |
| Reselect | ⌃⌘D |
| Show/Hide Selection | ⌃⌘H |
| Nudge selection 1 px / 10 px | arrows / ⇧+arrows |
| Deselect | Escape |
| New Layer | ⇧⌘N |
| New Layer with Selection / Cut Selection | ⌘J / ⇧⌘J |
| Duplicate Layer | ⇧⌘D |
| Delete Layer | ⌘Delete |
| Rename Layer | ⇧⌘R |
| Lock / Unlock Layer | ⌘/ |
| Merge Down | ⇧⌘M |
| Center Layer | ⇧⌘C |
| Clear Layer / with Primary / with Secondary | Delete / ⇧Delete / ⌥Delete |
| Select Next Layer Up / Down | ⌘↑ / ⌘↓ |
| Move Layer Up / Down | ⌥⌘] / ⌥⌘[ |
| Bring to Front / Send to Back | ⇧⌘] / ⇧⌘[ |
| Nudge layer | ⇧+arrows |
| Flip Layer Horizontally / Vertically | H / V |
| Rotate Layer Left / Right | ⌘[ / ⌘] |
| Group | ⌘G |
| Ungroup | ⇧⌘G |
| Resize Canvas… | ⌥⌘C |
| Resize Image… | ⌥⌘I |
| Pixel Aspect Ratio… | ⌥⌘R |
| Flip Canvas Horizontally / Vertically | ⇧H / ⇧V |
| Rotate Canvas Left / Right | ⌃⌘[ / ⌃⌘] |
| Nudge Canvas | ⌥⇧+arrows |
| Shift Tile (tileset mode) | ⌃⌥+arrows |
| Wrap Tiles (tileset mode) | ⌃⌘W |
| Show Grid | ⌘' |
| Toggle Zoom | Z |
| Zoom In / Out | ⌘+ / ⌘− |
| Zoom to Fit / Zoom to 100% | ⌘0 / ⌘1 |
| Zoom to Tile (tileset mode) | ⇧⌘0 |
| Show/Hide Inspector | ⇧⌘L |
| Show/Hide Preview | ⇧⌘P |
| New Preview Window | ⌥⌘P |
| Show/Hide Coordinates | ⌥⌘K |
| Show/Hide Timeline | ⌃⌘T |
| Show/Hide Metadata | ⌃⌘M |
| Composite / Onion Skin / Solo / Tileset / Animation mode | Control+1–5 (Mode menu) |
| Select vector object | V, then click |
| Draw vector poly line | B |
| Enter node-edit mode | double-click a path with Vector Select |
| Insert node | click path outline between two nodes |
| Remove selected node | Delete |